Johnson's Calm-Eze tablets are a natural dietary supplement designed to help calm and soothe nervous or hyperactive dogs and cats. Contain essential amino acids (like L-Tryptophan) and vitamins (such as Niacin, B6, E), which are believed to help naturally reduce anxiety. L-Tryptophan is a precursor to serotonin, a neurotransmitter that affects mood, anxiety, and happiness. Designed to calm pets without causing drowsiness.
They are particularly useful during times of stress, such as thunderstorms, fireworks, travel, or to help manage aggressive or territorial behaviors. 
Separation anxiety in dogs can be eased with the hugely popular Calm-Eze Anti Anxiety Travel Tablets for cats and dogs. Excellent for use with anxious or nervous dogs and cats. Helps to calm and soothe nervers and hyperactive pets, particularly useful when travelling. Also recommended for use during times of stress caused by separation, excitement, thunderstorms, fireworks, etc and work well in soothing agressive or territorial behaviour. These tablets are a natural dietary supplement containing amino-acids, vitamans and minerals and is safe to use, designed and created by veterinary practitioners. 
Dosage and Directions Cats Small Dogs 1 tablet, twice daily Medium Breeds 2 tablets, twice daily Large Breeds 3 tablets, twice daily Issue the number of tablets for your pet as indicated above in the morning and in the evening mixed in with food.
Natural dietary supplement: Contains essential amino-acids, vitamins, and minerals.
Helps calm and soothe: Intended to reduce nervousness and hyperactivity.
Suitable for stressful situations: Ideal for events like thunderstorms, fireworks, travel, and managing aggressive/territorial behavior.
For dogs and cats: Can be given to both cats and dogs. 
Each 255mg tablet contains:
L-tryptophan (20mg): An essential amino acid found in foods like red meat and poultry, known to influence mood and anxiety.
Niacin (10mg)
Vitamin B6 (0.1mg)
Zinc (0.1mg)
Pantothenic acid (0.05mg)
Vitamin A (Retinol Equivalent) (0.01mg)
Vitamin D3 (Cholecalciferol) (0.0001mg)
Selenium (0.0001mg)
Vitamin E (DL-Alpha Tocopherol Equiv) (0.5 IU) 
Customer reviews for Johnsons Calm-Eze tablets are mixed. Some users have reported positive results, particularly for calming pets during stressful events like fireworks or travel, and some have noted improved sleep. However, other users have found the tablets to be ineffective. 
Key points to remember include: do not exceed the recommended dose, the product is for animal use only, keep out of reach of children, and store in a dry place below 25°C.